HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: GPS2 (Q13227)
G protein pathway suppressor 2 (GPS-2)
Gene: GPS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 14527417, 12628926, 11931768, 26186194, 28514442, 33961781, unassigned3799
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains GPS2_interact~G_path_suppress
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2440
Hs

1 327
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025