HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 779
+	Hs
		280045 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		280051 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1225208 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOL2_MOUSE (1-779): 2.27e-58: 214: 86.17
+	Mm
		1257405 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Mm
		1257408 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOL1_MOUSE (1-761): 1.46e-38: 156: 38.96
+	Hs
		1119035 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1300698 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1020172 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1118998 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1246447 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		1021508 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		1199783 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1222264 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Hs
		1222248 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AMOL1_HUMAN (1-766): 4.56e-42: 167: 40.22
+	Mm
		1145448 PTN13_MOUSE (66-600): 1.52e-21: 105: 14.31		AMOT_MOUSE (1-661): 2.13e-38: 156: 38.02
+	Hs
		724926 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		MYH9_HUMAN (16-773): 4.81e-28: 123: 9.57
+	Hs
		1300684 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Hs
		1020232 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Hs
		1252532 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Mm
		936586 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		ROCK2_MOUSE (307-661): 3.25e-12: 72.4: 17.02