HitPredict

Interactor 1: NEUL1 (O76050)
E3 ubiquitin-protein ligase NEURL1 (EC 2.3.2.27) (Neuralized-like protein 1A) (h-neu) (h-neuralized 1) (RING finger protein 67) (RING-type E3 ubiquitin transferase NEURL1)
Gene: NEURL1

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 574 Hs			1 183
+	Hs
		282379 NEUL1_HUMAN (1-574): 0: 699: 100.00		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Mm
		56811 A2A5J5_MOUSE (50-157): 3.34e-35: 135: 32.41		UB2D1_MOUSE (7-150): 2.2e-72: 216: 32.43
+	At
		715118 LUL3_ARATH (414-570): 1.14e-32: 131: 19.62		UBC8_ARATH (7-151): 2.63e-72: 216: 30.20
+	At
		1195870 LUL3_ARATH (414-570): 1.14e-32: 131: 19.62		UBC29_ARATH (7-149): 5.9e-69: 208: 30.61
+	Hs
		909026 NEUL2_HUMAN (268-406): 1.45e-34: 134: 21.83		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00
+	Hs
		230183 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08
+	Hs
		230132 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Dm
		639392 DIAP1_DROME (440-573): 3.31e-23: 104: 19.40		UBCD1_DROME (7-150): 3.09e-72: 216: 29.73
+	Hs
		230126 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		919746 MEX3C_HUMAN (449-572): 3.76e-21: 99.5: 18.38		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		230131 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		919845 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		895820 MEX3B_HUMAN (455-572): 2.83e-22: 102: 19.12		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		849431 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Zm
		9310 A0A1D6EW17_MAIZE (464-570): 1.71e-21: 100: 28.04		A0A1D6NGW9_MAIZE (7-146): 2.15e-70: 214: 29.17
+	Hs
		895808 MEX3C_HUMAN (449-572): 3.76e-21: 99.5: 18.38		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		895897 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		230127 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		851881 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Ce
		1089233 Q17911_CAEEL (394-570): 6.28e-30: 125: 20.22		Q9TZ69_CAEEL (31-149): 3.48e-22: 90.1: 33.61