HitPredict

Interactor 1: TAF5L (O75529)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta)
Gene: TAF5L

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Histone~WD40
Common GO terms	GO:0005634 - nucleus GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 143
+	Hs
		845317 LIS1_HUMAN (86-498): 2.18e-80: 260: 14.32		H2A2A_HUMAN (1-129): 7.03e-66: 197: 91.47
+	Hs
		634052 FBXW7_HUMAN (299-588): 6.08e-72: 246: 21.05		H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70
+	Hs
		502431 DAW1_HUMAN (372-588): 2.46e-64: 218: 28.44		H2A1_HUMAN (1-129): 7.6e-66: 197: 91.47
+	Hs
		1232708 SNR40_HUMAN (418-588): 7.79e-40: 150: 26.59		H2A2A_HUMAN (1-129): 7.03e-66: 197: 91.47
+	Hs
		277777 SNR40_HUMAN (418-588): 7.79e-40: 150: 26.59		H2AY_HUMAN (1-142): 1.75e-61: 194: 60.69
+	Hs
		591570 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00
+	Hs
		261418 TBL1X_HUMAN (141-373): 4.1e-22: 102: 10.37		H2A2A_HUMAN (1-129): 7.03e-66: 197: 91.47
+	Hs
		418917 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		H2A1B_HUMAN (1-129): 8.38e-66: 197: 90.70
+	Hs
		277626 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		H2AY_HUMAN (1-142): 1.75e-61: 194: 60.69