HitPredict

Interactor 1: CDKF1 (O80345)
Cyclin-dependent kinase F-1 (CDKF;1) (EC 2.7.11.22) (EC 2.7.11.23) (CDK-activating kinase 1-At) (CAK1-At)
Gene: CDKF-1

Interactor 2: CKS2 (Q9SJJ5)
Cyclin-dependent kinases regulatory subunit 2
Gene: CKS2

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20407024
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007049 - cell cycle GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 479 At			1 83
+	At
		188135 CDKF1_ARATH (1-479): 1.11e-128: 383: 100.00		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		1321252 CDKD2_ARATH (9-223): 3.07e-61: 205: 27.93		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	Hs
		625283 CDK2_HUMAN (18-224): 4.04e-69: 224: 28.04		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		625164 CDK2_HUMAN (18-224): 4.04e-69: 224: 28.04		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		188163 CDKD2_ARATH (9-223): 3.07e-61: 205: 27.93		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		895413 CDK3_HUMAN (18-206): 1.04e-64: 213: 31.12		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		706796 CDK3_HUMAN (18-206): 1.04e-64: 213: 31.12		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		1321299 CDKD1_ARATH (14-171): 7.7e-19: 90.1: 36.75		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		1338686 CDKD3_ARATH (14-171): 2.28e-17: 85.5: 36.75		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		1228093 CKB22_ARATH (21-169): 8.33e-16: 80.1: 33.54		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		621728 CDKA1_ARATH (20-169): 5.04e-15: 77.4: 37.50		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188168 CDKD3_ARATH (14-171): 2.28e-17: 85.5: 36.75		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		188157 CKB22_ARATH (21-169): 8.33e-16: 80.1: 33.54		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		414843 CDK1_HUMAN (21-169): 9.34e-19: 88.6: 35.90		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		188136 CDKA1_ARATH (20-169): 5.04e-15: 77.4: 37.50		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Hs
		414778 CDK1_HUMAN (21-169): 9.34e-19: 88.6: 35.90		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Dm
		618415 CDK1_DROME (21-169): 5.2e-16: 80.5: 34.62		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Sp
		383445 CDK1_SCHPO (18-169): 7.39e-17: 82.8: 34.94		CKS1_SCHPO (1-80): 1.02e-34: 115: 46.07
+	Dm
		618387 CDK1_DROME (21-169): 5.2e-16: 80.5: 34.62		CKS1_DROME (3-71): 4.92e-35: 115: 68.12