HitPredict

Interactor 1: A0A0C4DFT8 (A0A0C4DFT8)
Jade family PHD finger 2
Gene: JADE2

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EPL1~ING
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 791 Hs			1 249
+	Hs
		1446917 JADE2_HUMAN (1-791): 0: 794: 99.87		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		2849 A0A0C4DFT8_HUMAN (1-791): 0: 800: 100.00		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		1361585 JADE2_HUMAN (1-791): 0: 794: 99.87		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		1234203 JADE1_HUMAN (4-791): 0: 697: 47.55		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		1234190 JADE1_HUMAN (4-791): 0: 697: 47.55		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		1446914 JADE2_HUMAN (1-791): 0: 794: 99.87		ING3_HUMAN (180-249): 2.4e-32: 123: 57.14
+	Hs
		342370 BRD1_HUMAN (6-776): 0: 594: 21.70		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		1365558 JADE3_HUMAN (4-768): 0: 586: 40.65		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		936683 BRPF1_HUMAN (6-743): 0: 570: 20.03		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		342273 BRD1_HUMAN (6-776): 0: 594: 21.70		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		1361564 JADE3_HUMAN (4-768): 0: 586: 40.65		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		936664 BRPF1_HUMAN (6-743): 0: 570: 20.03		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Hs
		1461509 BRPF3_HUMAN (2-767): 7.28e-168: 518: 20.07		ING4_HUMAN (1-249): 7.53e-98: 287: 100.00
+	Hs
		1361595 BRPF3_HUMAN (2-767): 7.28e-168: 518: 20.07		ING5_HUMAN (1-249): 6.73e-86: 257: 67.87
+	Dm
		1262319 BRDH_DROME (22-720): 1e-168: 526: 24.05		ING5_DROME (1-249): 1.5e-73: 227: 46.34
+	Hs
		1365554 JADE3_HUMAN (4-768): 0: 586: 40.65		ING3_HUMAN (180-249): 2.4e-32: 123: 57.14
+	Hs
		936682 BRPF1_HUMAN (6-743): 0: 570: 20.03		ZMYD8_HUMAN (125-244): 1.27e-19: 89.6: 22.39
+	Hs
		1452098 BRPF3_HUMAN (2-767): 7.28e-168: 518: 20.07		ING3_HUMAN (180-249): 2.4e-32: 123: 57.14
+	Sc
		1064194 NTO1_YEAST (72-516): 4.98e-107: 346: 24.70		YNG1_YEAST (10-245): 1.12e-42: 146: 22.88