HitPredict - High confidence protein-protein interactions

Interactor 1: PGRP1 (O75594)
Peptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S)
Gene: PGLYRP1

Interactor 2: PGRP1 (O75594)
Peptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S)
Gene: PGLYRP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16354652
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Amidase_2~Amidase_2
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006955 - immune response GO:0008270 - zinc ion binding GO:0008745 - N-acetylmuramoyl-L-alanine amidase activity and 20 others more... GO:0009253 - peptidoglycan catabolic process GO:0016019 - peptidoglycan immune receptor activity GO:0016045 - detection of bacterium GO:0030544 - Hsp70 protein binding GO:0031640 - killing of cells of another organism GO:0032689 - negative regulation of type II interferon production GO:0032827 - negative regulation of natural killer cell differentiation involved in immune response GO:0035580 - specific granule lumen GO:0042742 - defense response to bacterium GO:0042834 - peptidoglycan binding GO:0045087 - innate immune response GO:0048018 - receptor ligand activity GO:0050728 - negative regulation of inflammatory response GO:0050830 - defense response to Gram-positive bacterium GO:0051701 - biological process involved in interaction with host GO:0060090 - molecular adaptor activity GO:0061844 - antimicrobial humoral immune response mediated by antimicrobial peptide GO:0070062 - extracellular exosome GO:0097013 - phagocytic vesicle lumen GO:1904724 - tertiary granule lumen
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	196
Hs

1	196

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Last updated: 11Aug2025