Protein: PGPLE
Peptidoglycan-recognition protein LE

Gene: PGPLE, PGRP-LE
Organism: Drosophila melanogaster
Interactions: 140
UniProt ID: Q9VXN9

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0008340 - determination of adult lifespan
GO:0042742 - defense response to bacterium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1488358

PGPLE
Peptidoglycan-recognition protein LE

4

9

Small-scale

0.896

High

1488364

Q9W2E6
Poor Imd response upon knock-in, isoform A

3

1

Small-scale

0.640

High

1478098

BHMT
Betaine-homocysteine S-methyltransferase

2

0

High-throughput

0.569

High

1306453

INDRA
Zinc finger protein indra

1

0

High-throughput

0.486

High

121573

M9PFI0
CCR4-NOT transcription complex subunit 4

1

1

High-throughput

0.479

High

305540

O77430
GEO01111p1

1

2

High-throughput

0.479

High

538291

HSP7D
Heat shock 70 kDa protein cognate 4

1

3

High-throughput

0.479

High

554106

TCPA
T-complex protein 1 subunit alpha

1

6

High-throughput

0.479

High

559838

EF2
Eukaryotic translation elongation factor 2

1

1

High-throughput

0.479

High

604371

CATA
Catalase

1

1

High-throughput

0.479

High

633083

NCD
Protein claret segregational

1

1

High-throughput

0.479

High

715347

HSP7A
Heat shock 70 kDa protein cognate 1

1

3

High-throughput

0.479

High

834829

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.479

High

852535

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.479

High

963891

SODC
Superoxide dismutase [Cu-Zn]

1

2

High-throughput

0.479

High

1175956

ADT
ADP,ATP carrier protein

1

1

High-throughput

0.479

High

1266746

IMD
Protein immune deficiency

1

1

Small-scale

0.479

High

1346206

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

1

High-throughput

0.479

High

1440095

JUPIT
Microtubule-associated protein Jupiter

1

1

High-throughput

0.479

High

1464051

PRDX2
Peroxiredoxin 2

1

1

High-throughput

0.479

High

1469725

Q9VBU9
40S ribosomal protein S27

1

1

High-throughput

0.479

High

1476318

Q9VHL2
T-complex protein 1 subunit eta

1

2

High-throughput

0.479

High

1479268

Q9VK69
T-complex protein 1 subunit delta

1

2

High-throughput

0.479

High

1481660

CUP
Protein cup

1

1

High-throughput

0.479

High

1483115

Q9VP57
LD15904p

1

1

High-throughput

0.479

High

1488370

RHGF
Rho GTPase-activating protein Graf

1

1

High-throughput

0.479

High

118638

M9NF18
Uncharacterized protein, isoform D

1

0

High-throughput

0.458

High

1038264

IF4A
Eukaryotic initiation factor 4A

1

0

High-throughput

0.458

High

1069319

Q0E8J0
MOG interacting and ectopic P-granules protein 1

1

0

High-throughput

0.458

High

1172269

DNAJ1
DnaJ protein homolog 1

1

0

High-throughput

0.458

High

1174391

CP190
Centrosome-associated zinc finger protein Cp190

1

0

High-throughput

0.458

High

1265671

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

1468838

RING1
E3 ubiquitin-protein ligase RING1

1

0

High-throughput

0.458

High

1470159

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

0

High-throughput

0.458

High

1470770

VRET
Protein vreteno

1

0

High-throughput

0.458

High

1474466

Q9VG78
Protein partner of snf, isoform A

1

0

High-throughput

0.458

High

1475570

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.458

High

1480306

SOYB
Putative ATP-dependent RNA helicase SoYb

1

0

High-throughput

0.458

High

1486667

FRL
Formin-like protein

1

0

High-throughput

0.458

High

1488196

NU153
Nuclear pore complex protein Nup153

1

0

High-throughput

0.458

High

1488360

Q9VZF2
LD05244p

1

0

High-throughput

0.458

High

1488366

Q9W2U7
LP18708p

1

0

High-throughput

0.458

High

53082

A1Z7K2
FI03455p

1

1

High-throughput

0.437

High

56393

ZASP
PDZ and LIM domain protein Zasp

1

1

High-throughput

0.437

High

57895

A1ZB77
Uncharacterized protein, isoform J

1

1

High-throughput

0.437

High

146160

CH60A
Heat shock protein 60A

1

3

High-throughput

0.437

High

197896

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.437

High

387006

ACT2
Actin-42A

1

5

High-throughput

0.437

High

387080

ACT4
Actin, larval muscle

1

5

High-throughput

0.437

High

427005

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.437

High

444109

TBA1
Tubulin alpha-1 chain

1

5

High-throughput

0.437

High

444132

TBA2
Tubulin alpha-2 chain

1

5

High-throughput

0.437

High

444155

TBA3
Tubulin alpha-3 chain

1

5

High-throughput

0.437

High

475843

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.437

High

476488

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.437

High

534388

ACT5
Actin-87E

1

5

High-throughput

0.437

High

534507

ACT1
Actin-5C

1

5

High-throughput

0.437

High

607517

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.437

High

652127

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

1

High-throughput

0.437

High

715385

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.437

High

770983

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

856486

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.437

High

875314

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.437

High

891992

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.437

High

896173

MSL3
Protein male-specific lethal-3

1

2

High-throughput

0.437

High

898360

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.437

High

921007

ACT3
Actin-57B

1

5

High-throughput

0.437

High

938946

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

1013250

STIM
Stromal interaction molecule homolog

1

1

High-throughput

0.437

High

1014462

ACT6
Actin, indirect flight muscle

1

5

High-throughput

0.437

High

1055756

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

1172913

RS5A
Small ribosomal subunit protein uS7A

1

1

High-throughput

0.437

High

1174635

TBB1
Tubulin beta-1 chain

1

2

High-throughput

0.437

High

1260782

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

1264056

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.437

High

1265876

Q7K3J0
T-complex protein 1 subunit theta

1

2

High-throughput

0.437

High

1267287

Q7KKI0
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.437

High

1286194

LIG
Protein lingerer

1

1

High-throughput

0.437

High

1304067

SLE
Protein slender lobes

1

1

High-throughput

0.437

High

1376913

CATL1
Cathepsin L1

1

1

High-throughput

0.437

High

1457991

NH2L1
NHP2-like protein 1 homolog

1

3

High-throughput

0.437

High

1463945

RUVB2
RuvB-like helicase 2

1

1

High-throughput

0.437

High

1465307

PDIA6
Protein disulfide-isomerase A6 homolog

1

2

High-throughput

0.437

High

1465796

HCF
Host cell factor

1

1

High-throughput

0.437

High

1473777

RS5B
Small ribosomal subunit protein uS7B

1

1

High-throughput

0.437

High

1473829

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.437

High

1475413

SLEL
Slender lobes-like protein

1

1

High-throughput

0.437

High

1475444

RUVB1
RuvB-like helicase 1

1

1

High-throughput

0.437

High

1478335

Q9VJD1
Glucosidase 2 subunit beta

1

1

High-throughput

0.437

High

1481891

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

3

High-throughput

0.437

High

1487143

Q9VV75
AT02348p

1

2

High-throughput

0.437

High

1488359

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

2

High-throughput

0.437

High

1488361

Q9W0A8
FI01658p

1

1

High-throughput

0.437

High

1488362

Q9W1B9
Large ribosomal subunit protein uL11

1

1

High-throughput

0.437

High

1488363

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.437

High

1488367

RS28
Small ribosomal subunit protein eS28

1

1

High-throughput

0.437

High

1488368

Q9W392
T-complex protein 1 subunit beta

1

4

High-throughput

0.437

High

929312

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

928911

WEE1
Wee1-like protein kinase

2

0

High-throughput

0.310

High

654916

MA205
205 kDa microtubule-associated protein

2

0

High-throughput

0.305

High

1474091

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.265

Low

57142

A1ZAU6
FI05912p

1

0

High-throughput

0.249

Low

69263

A8JUU3
Secretory 16, isoform D

1

0

High-throughput

0.249

Low

95312

E1JIM0
Non-specific lethal 1, isoform E

1

0

High-throughput

0.249

Low

119972

M9PBW9
Rhea, isoform G

1

0

High-throughput

0.249

Low

234514

CTBP
C-terminal-binding protein

1

0

High-throughput

0.249

Low

583648

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.249

Low

628973

OTE
Otefin

1

0

High-throughput

0.249

Low

870629

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.249

Low

1019561

MIC60
MICOS complex subunit Mic60

1

0

High-throughput

0.249

Low

1070034

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.249

Low

1261598

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1264825

Q7K180
LD02709p

1

0

High-throughput

0.249

Low

1266344

DGT5
Augmin complex subunit dgt5

1

0

High-throughput

0.249

Low

1269524

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.249

Low

1285549

Q86BB4
Transforming acidic coiled-coil protein, isoform E

1

0

High-throughput

0.249

Low

1321349

LVA
Protein lava lamp

1

0

High-throughput

0.249

Low

1344640

Q8SYU0
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

1465897

ANLN
Anillin

1

0

High-throughput

0.249

Low

1467292

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1467325

DJ1B
Protein dj-1beta

1

0

High-throughput

0.249

Low

1467872

S39AD
Zinc transporter ZIP13 homolog

1

0

High-throughput

0.249

Low

1468041

Q9VAJ2
Mitotic checkpoint protein BUB3

1

0

High-throughput

0.249

Low

1471299

Q9VD58
Isocitric dehydrogenase subunit beta

1

0

High-throughput

0.249

Low

1471574

Q9VDH8
Ribosomal protein S30, isoform A

1

0

High-throughput

0.249

Low

1473333

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

0

High-throughput

0.249

Low

1476198

Q9VHH8
Beag

1

0

High-throughput

0.249

Low

1476756

Q9VHT6
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

1477208

Q9VI56
GEO05313p1

1

0

High-throughput

0.249

Low

1478660

NC2B
Protein Dr1

1

0

High-throughput

0.249

Low

1478826

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.249

Low

1481249

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.249

Low

1483615

Q9VPU7
Arouser, isoform C

1

0

High-throughput

0.249

Low

1486169

R10AB
Large ribosomal subunit protein uL1

1

0

High-throughput

0.249

Low

1487972

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.249

Low

1488012

Q9VWS3
Rab11 interacting protein, isoform A

1

0

High-throughput

0.249

Low

1488049

CREBB
Cyclic AMP response element-binding protein B

1

0

High-throughput

0.249

Low

1488365

SGF29
SAGA-associated factor 29kDa

1

0

High-throughput

0.249

Low

1488369

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025