Protein: PGPLC
Peptidoglycan-recognition protein LC (Immune response deficient 7 protein)

Gene: PGPLC, PGRP-LC
Organism: Drosophila melanogaster
Interactions: 83
UniProt ID: Q9GNK5

Gene Ontology (top 5):
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0002920 - regulation of humoral immune response
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0006963 - positive regulation of antibacterial peptide biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1427708

PGPLC
Peptidoglycan-recognition protein LC

5

8

Small-scale

0.925

High

1343961

PGPLF
Peptidoglycan-recognition protein LF

1

8

Small-scale

0.692

High

1427738

Q9W2E6
Poor Imd response upon knock-in, isoform A

5

1

Small-scale

0.648

High

1266710

IMD
Protein immune deficiency

3

1

Small-scale

0.640

High

1427728

PGPSD
Peptidoglycan-recognition protein SD

1

8

Small-scale

0.618

High

1069242

Q0E8F8
Fork head transcription factor long isoform

1

0

High-throughput

0.486

High

1266464

Q7K4J7
LD36653p

1

0

High-throughput

0.486

High

1427723

SMBT
Polycomb protein Sfmbt

1

0

High-throughput

0.486

High

120159

M9PCH6
Venom dipeptidyl peptidase 4

1

1

High-throughput

0.481

High

121567

M9PFI0
CCR4-NOT transcription complex subunit 4

1

1

High-throughput

0.479

High

538253

HSP7D
Heat shock 70 kDa protein cognate 4

1

3

High-throughput

0.479

High

604346

CATA
Catalase

1

1

High-throughput

0.479

High

652067

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

1

High-throughput

0.479

High

963859

SODC
Superoxide dismutase [Cu-Zn]

1

2

High-throughput

0.479

High

1013235

STIM
Stromal interaction molecule homolog

1

1

High-throughput

0.479

High

1346188

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

1

High-throughput

0.479

High

1427711

Q9V3N6
Transmembrane 9 superfamily member

1

1

Small-scale

0.479

High

1427716

Q9VBU9
40S ribosomal protein S27

1

1

High-throughput

0.479

High

1427721

Q9VIK1
Transmembrane 9 superfamily member

1

1

Small-scale

0.479

High

1427727

Q9VP57
LD15904p

1

1

High-throughput

0.479

High

1427742

RHGF
Rho GTPase-activating protein Graf

1

1

High-throughput

0.479

High

1173332

DIAP2
Death-associated inhibitor of apoptosis 2

1

0

Small-scale

0.458

High

1427733

Q9VYN4
Ionotropic receptor 11a

1

0

High-throughput

0.458

High

1427729

Q9VUH1
Venom dipeptidyl peptidase 4

1

1

High-throughput

0.457

High

56370

ZASP
PDZ and LIM domain protein Zasp

1

1

High-throughput

0.437

High

57810

A1ZB77
Uncharacterized protein, isoform J

1

1

High-throughput

0.437

High

146130

CH60A
Heat shock protein 60A

1

3

High-throughput

0.437

High

197805

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.437

High

426996

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.437

High

444091

TBA1
Tubulin alpha-1 chain

1

5

High-throughput

0.437

High

444122

TBA2
Tubulin alpha-2 chain

1

5

High-throughput

0.437

High

444147

TBA3
Tubulin alpha-3 chain

1

5

High-throughput

0.437

High

475814

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.437

High

559811

EF2
Eukaryotic translation elongation factor 2

1

1

High-throughput

0.437

High

607493

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.437

High

633074

NCD
Protein claret segregational

1

1

High-throughput

0.437

High

715402

HSP7E
Heat shock 70 kDa protein cognate 5

1

5

High-throughput

0.437

High

770963

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

834820

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.437

High

852503

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.437

High

856469

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.437

High

875246

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.437

High

891982

TAF6
Transcription initiation factor TFIID subunit 6

1

1

High-throughput

0.437

High

896157

MSL3
Protein male-specific lethal-3

1

2

High-throughput

0.437

High

898334

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.437

High

938921

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

1055718

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

1175943

ADT
ADP,ATP carrier protein

1

1

High-throughput

0.437

High

1260754

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

1264026

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.437

High

1286180

LIG
Protein lingerer

1

1

High-throughput

0.437

High

1376888

CATL1
Cathepsin L1

1

1

High-throughput

0.437

High

1427709

JUPIT
Microtubule-associated protein Jupiter

1

1

High-throughput

0.437

High

1427710

NH2L1
NHP2-like protein 1 homolog

1

3

High-throughput

0.437

High

1427712

PRDX2
Peroxiredoxin 2

1

1

High-throughput

0.437

High

1427713

PDIA6
Protein disulfide-isomerase A6 homolog

1

2

High-throughput

0.437

High

1427714

HCF
Host cell factor

1

1

High-throughput

0.437

High

1427719

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.437

High

1427722

Q9VJD1
Glucosidase 2 subunit beta

1

1

High-throughput

0.437

High

1427724

CUP
Protein cup

1

1

High-throughput

0.437

High

1427725

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

3

High-throughput

0.437

High

1427732

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

2

High-throughput

0.437

High

1427734

Q9W0A8
FI01658p

1

1

High-throughput

0.437

High

1427736

Q9W1B9
Large ribosomal subunit protein uL11

1

1

High-throughput

0.437

High

1427737

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.437

High

1427739

RS28
Small ribosomal subunit protein eS28

1

1

High-throughput

0.437

High

1427740

Q9W392
T-complex protein 1 subunit beta

1

4

High-throughput

0.437

High

1427718

Q9VF37
Crossover suppressor on 3 of Gowen

1

0

High-throughput

0.265

Low

61234

A2VEJ9
IP17766p

1

0

High-throughput

0.249

Low

198159

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.249

Low

304653

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.249

Low

356379

O97102
Small ubiquitin-related modifier

1

0

High-throughput

0.249

Low

1262300

Q7JVK8
GEO08987p1

1

0

High-throughput

0.249

Low

1269843

Q7KUQ6
Limpet, isoform K

1

0

High-throughput

0.249

Low

1427715

Q9V9Q4
LD43819p

1

0

High-throughput

0.249

Low

1427720

Q9VHN7
transketolase

1

0

High-throughput

0.249

Low

1427726

Q9VNA3
GH21273p

1

0

High-throughput

0.249

Low

1427730

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.249

Low

1427731

Q9VXF8
Eukaryotic translation initiation factor 4H

1

0

High-throughput

0.249

Low

1427735

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.249

Low

1427741

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.249

Low

1427717

INO80
Chromatin-remodeling ATPase INO80

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025