HitPredict

Interactor 1: BCL6B (O88282)
B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein)
Gene: BCL6B

Interactor 2: BCL6 (P41183)
B-cell lymphoma 6 protein homolog
Gene: BCL6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 20211142, 9632807, 16331266
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 474
Mm

1 707
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024