HitPredict

Interactor 1: KCNJ1 (O88335)
ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1)
Gene: KCNJ1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Mm			1 724
+	Hs
		929762 KCNJ2_HUMAN (10-371): 0: 557: 43.53		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Hs
		942342 KCJ12_HUMAN (12-370): 0: 544: 45.56		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Rn
		677769 KCJ12_RAT (12-370): 0: 539: 45.56		DLG4_RAT (1-724): 0: 671: 99.45
+	Mm
		852403 KCNJ4_MOUSE (16-365): 0: 512: 42.97		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		1143540 Q9QYK8_MOUSE (16-365): 1.27e-179: 507: 42.97		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		1054724 KCJ12_HUMAN (12-370): 0: 544: 45.56		DLG3_HUMAN (28-724): 0: 600: 64.92
+	Hs
		929764 KCNJ2_HUMAN (10-371): 0: 557: 43.53		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Rn
		852399 KCJ12_RAT (12-370): 0: 539: 45.56		DLG3_RAT (20-724): 0: 585: 63.94
+	Hs
		1021490 KCJ12_HUMAN (12-370): 0: 544: 45.56		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Rn
		1144015 KCNJ2_RAT (10-371): 0: 555: 43.25		DLG1_RAT (8-724): 0: 564: 66.98
+	Hs
		80982 KCJ18_HUMAN (12-370): 0: 539: 45.28		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Rn
		852397 KCJ12_RAT (12-370): 0: 539: 45.56		DLG1_RAT (8-724): 0: 564: 66.98
+	Hs
		929767 KCNJ2_HUMAN (10-371): 0: 557: 43.53		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		1049947 KCJ12_HUMAN (12-370): 0: 544: 45.56		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Rn
		1144360 KCNJ2_RAT (10-371): 0: 555: 43.25		DLG2_RAT (234-580): 2.32e-17: 88.6: 19.55
+	Hs
		159210 KCJ12_HUMAN (12-370): 0: 544: 45.56		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Rn
		852398 KCJ12_RAT (12-370): 0: 539: 45.56		CSKP_RAT (31-271): 2.11e-20: 98.6: 14.80
+	Hs
		1054723 KCJ12_HUMAN (12-370): 0: 544: 45.56		DLG2_HUMAN (234-580): 8.36e-18: 90.1: 19.55
+	Rn
		852400 KCJ12_RAT (12-370): 0: 539: 45.56		DLG2_RAT (234-580): 2.32e-17: 88.6: 19.55
+	Hs
		1054729 KCJ12_HUMAN (12-370): 0: 544: 45.56		PALS2_HUMAN (22-193): 2.91e-13: 75.1: 15.52