HitPredict

Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 757 Mm			1 734
+	Hs
		158377 IKKB_HUMAN (1-755): 0: 683: 92.05		UBC_HUMAN (77-724): 0: 790: 97.22
+	Mm
		476818 IKKA_MOUSE (1-742): 4.58e-173: 516: 48.87		UBC_MOUSE (1-734): 0: 912: 100.00
+	Hs
		167451 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		UBC_HUMAN (77-724): 0: 790: 97.22
+	Mm
		477048 IKKE_MOUSE (15-382): 1.64e-102: 332: 27.75		UBC_MOUSE (1-734): 0: 912: 100.00
+	Rn
		550163 KCC2D_RAT (4-300): 7.41e-94: 304: 25.08		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		476524 TBK1_HUMAN (15-407): 2.11e-105: 340: 26.23		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475745 IKKE_HUMAN (15-382): 5.99e-104: 336: 27.75		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475723 KCC2D_HUMAN (4-300): 2.85e-94: 304: 25.08		UBC_HUMAN (77-724): 0: 790: 97.22
+	Mm
		250791 ULK1_MOUSE (10-222): 4.66e-29: 126: 35.14		UBC_MOUSE (1-734): 0: 912: 100.00
+	Rn
		250479 KCC1B_RAT (15-254): 6.99e-26: 111: 31.02		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		262227 ULK1_HUMAN (9-222): 7.53e-30: 129: 34.98		UBC_HUMAN (77-724): 0: 790: 97.22
+	At
		1091642 CDPKB_ARATH (2-509): 4.56e-148: 443: 16.31		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Sc
		419769 SNF1_YEAST (12-373): 2.8e-104: 334: 25.66		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	At
		1091633 CDPK5_ARATH (7-482): 1.03e-141: 429: 16.98		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091676 CDPK3_ARATH (15-493): 1.14e-141: 428: 16.46		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1092417 CDPKQ_ARATH (7-483): 8.67e-141: 424: 16.53		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091641 KIN10_ARATH (14-411): 2.75e-96: 309: 23.02		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		955189 KIN11_ARATH (14-301): 2.16e-94: 304: 25.09		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1259032 CDPKD_ARATH (8-510): 6.59e-139: 421: 16.08		P4KG4_ARATH (235-423): 6.92e-19: 92.9: 33.16
+	Hs
		475222 TBK1_HUMAN (15-407): 2.11e-105: 340: 26.23		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70