Interactor 1: AXIN2 (O88566)
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Gene: AXIN2
Interactor 2: Q8BNP7 (Q8BNP7)
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein
Gene: Apc
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.713 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9554852 |
| Identification Methods | two hybrid, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arm~Axin_b-cat_bind |
| Common GO terms | GO:0008013 - beta-catenin binding GO:0030877 - beta-catenin destruction complex GO:0090090 - negative regulation of canonical Wnt signaling pathway |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
