HitPredict

Interactor 1: BECN1 (O88597)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: PK3C3 (Q6PF93)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3)
Gene: Pik3c3

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.724

The method score is based on:

Property Details
Experiments 23569248, 27398911, 19270693, 23332761, 24849286, 23974797
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0005737 - cytoplasm
GO:0005776 - autophagosome
GO:0006622 - protein targeting to lysosome
and 15 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 448
Mm

1 887
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024