Interactor 1: CRADD (O88843)
Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)
Gene: CRADD

Interactor 2: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11978827
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~Death, Death~Death
Common GO terms GO:0043065 - positive regulation of apoptotic process
GO:0070513 - death domain binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 199
Mm

1 656
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024