HitPredict

Interactor 1: SMC1 (O94383)
Structural maintenance of chromosomes protein 1 (Chromosome segregation protein smc1) (Cohesin complex subunit psm1)
Gene: psm1

Interactor 2: PDS5 (Q9HFF5)
Sister chromatid cohesion protein pds5 (Precocious dissociation of sisters protein 5)
Gene: PDS5

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26687354
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0007064 - mitotic sister chromatid cohesion GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1228 Sp			1 1205
+	Mm
		93884 SMC1A_MOUSE (1-1226): 1.97e-93: 328: 32.50		E9QPI5_MOUSE (11-1196): 0: 1226: 21.56
+	Hs
		1057273 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		PDS5A_HUMAN (11-1194): 0: 1221: 21.43
+	Mm
		1118817 SMC1A_MOUSE (1-1226): 1.97e-93: 328: 32.50		PDS5B_MOUSE (11-1202): 0: 1215: 21.96
+	Hs
		1057405 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		PDS5B_HUMAN (11-1202): 0: 1213: 21.92
+	Mm
		1149127 SMC1A_MOUSE (1-1226): 1.97e-93: 328: 32.50		PDS5A_MOUSE (11-1196): 0: 1208: 21.48
+	Xl
		292729 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		PD5AB_XENLA (10-1200): 0: 1201: 21.12
+	Xl
		292730 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		PD5AA_XENLA (7-1200): 0: 1201: 21.07
+	Mm
		93885 SMC3_MOUSE (3-1225): 2.53e-72: 266: 14.47		E9QPI5_MOUSE (11-1196): 0: 1226: 21.56
+	Xl
		292728 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Hs
		1100586 SMC3_HUMAN (3-1225): 3.12e-72: 265: 14.47		PDS5A_HUMAN (11-1194): 0: 1221: 21.43
+	Hs
		1345702 SMC3_HUMAN (3-1225): 3.12e-72: 265: 14.47		PDS5B_HUMAN (11-1202): 0: 1213: 21.92
+	Sp
		193880 SMC3_SCHPO (3-1220): 6.4e-68: 252: 15.30		PDS5_SCHPO (1-1205): 0: 1212: 100.00
+	Xl
		1117310 Q8AW91_XENLA (3-1225): 2.07e-70: 260: 14.62		PD5AB_XENLA (10-1200): 0: 1201: 21.12
+	Xl
		292739 SMC3_XENLA (3-1225): 1.56e-69: 257: 14.48		PD5AA_XENLA (7-1200): 0: 1201: 21.07
+	Xl
		292740 SMC3_XENLA (3-1225): 1.56e-69: 257: 14.48		PD5BB_XENLA (11-1201): 0: 1186: 21.75
+	Xl
		1115499 Q8AW91_XENLA (3-1225): 2.07e-70: 260: 14.62		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Xl
		292738 SMC3_XENLA (3-1225): 1.56e-69: 257: 14.48		PD5BA_XENLA (11-1201): 0: 1173: 21.45
+	Sc
		700799 SMC1_YEAST (1-1228): 2.12e-79: 287: 33.01		PDS5_YEAST (3-1197): 0: 976: 22.33
+	Sc
		810772 SMC3_YEAST (3-1219): 9.65e-66: 246: 16.04		PDS5_YEAST (3-1197): 0: 976: 22.33
+	Hs
		69118 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		A9IYQ1_HUMAN (1028-1202): 1.69e-36: 142: 23.44