HitPredict

Interactor 1: CD123 (O75794)
Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32)
Gene: CDC123

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37314216
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 336 Hs			1 411
+	Hs
		293458 CD123_HUMAN (1-336): 0: 567: 100.00		IF4A1_HUMAN (7-411): 1.4e-178: 505: 66.75
+	Hs
		293166 CD123_HUMAN (1-336): 0: 567: 100.00		DDX5_HUMAN (25-411): 9.7e-134: 398: 30.63
+	Hs
		294114 CD123_HUMAN (1-336): 0: 567: 100.00		DDX17_HUMAN (14-411): 7.29e-132: 397: 30.79
+	Hs
		141235 CD123_HUMAN (1-336): 0: 567: 100.00		DDX3X_HUMAN (17-410): 7.28e-129: 387: 32.45
+	Hs
		293232 CD123_HUMAN (1-336): 0: 567: 100.00		DDX6_HUMAN (35-407): 1.16e-88: 278: 37.83