HitPredict

Interactor 1: PSA2 (O94579)
Probable proteasome subunit alpha type-2
Gene: pre8

Interactor 2: RPN6 (Q9P7S2)
Probable 26S proteasome regulatory subunit rpn6
Gene: RPN6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22187461
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~RPN6_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Sp			1 421
+	Dm
		771297 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSD11_DROME (1-419): 1.51e-104: 317: 52.61
+	Hs
		121689 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Dm
		1180708 PSA5_DROME (3-245): 2.73e-92: 273: 30.80		PSD11_DROME (1-419): 1.51e-104: 317: 52.61
+	Hs
		121685 PSA4_HUMAN (1-242): 4.28e-89: 265: 36.59		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Hs
		121719 PSA6_HUMAN (2-245): 8.12e-89: 264: 32.26		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Hs
		121684 PSA2_HUMAN (3-245): 2.06e-88: 263: 60.49		PSD11_HUMAN (1-419): 5.79e-106: 321: 53.79
+	Dm
		771305 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSMD6_DROME (27-419): 3.57e-81: 256: 13.86
+	Hs
		893638 PSA6_HUMAN (2-245): 8.12e-89: 264: 32.26		CSN2_HUMAN (11-417): 1.15e-93: 290: 20.53
+	Sc
		619525 PSA2_YEAST (1-245): 1.34e-89: 266: 66.40		RPN6_YEAST (4-419): 3.71e-90: 281: 47.55
+	Hs
		656232 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		638133 PSA4_HUMAN (1-242): 4.28e-89: 265: 36.59		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		893673 PSA6_HUMAN (2-245): 8.12e-89: 264: 32.26		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		637690 PSA2_HUMAN (3-245): 2.06e-88: 263: 60.49		PSMD6_HUMAN (25-419): 2.75e-87: 272: 14.53
+	Hs
		121942 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Dm
		1278633 PSA5_DROME (3-245): 2.73e-92: 273: 30.80		PSMD6_DROME (27-419): 3.57e-81: 256: 13.86
+	Hs
		121938 PSA4_HUMAN (1-242): 4.28e-89: 265: 36.59		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Hs
		121979 PSA6_HUMAN (2-245): 8.12e-89: 264: 32.26		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Hs
		121936 PSA2_HUMAN (3-245): 2.06e-88: 263: 60.49		PSD12_HUMAN (7-420): 2.44e-82: 261: 12.70
+	Dm
		771304 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		CSN4_DROME (50-413): 1.58e-66: 219: 15.13
+	Hs
		893660 PSA6_HUMAN (2-245): 8.12e-89: 264: 32.26		CSN1_HUMAN (11-419): 1.91e-71: 234: 12.09