HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 939
+	Hs
		294235 RECQ4_HUMAN (1-1208): 0: 794: 100.00		AP2A1_HUMAN (1-939): 0: 832: 78.47
+	Hs
		294672 RECQ4_HUMAN (1-1208): 0: 794: 100.00		AP2B1_HUMAN (36-933): 0: 607: 16.62
+	Hs
		294761 RECQ4_HUMAN (1-1208): 0: 794: 100.00		AP1B1_HUMAN (36-934): 0: 606: 17.35
+	Hs
		133807 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		AP2A1_HUMAN (1-939): 0: 832: 78.47
+	Sc
		416101 DED1_YEAST (410-849): 9.08e-110: 359: 16.06		AP3D_YEAST (51-603): 2.99e-19: 95.5: 21.21
+	Sc
		984221 HRQ1_YEAST (464-807): 6.14e-13: 75.9: 24.67		AP3D_YEAST (51-603): 2.99e-19: 95.5: 21.21