HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 2157
+	Hs
		133925 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		294506 RECQ4_HUMAN (1-1208): 0: 794: 100.00		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		295005 RECQ4_HUMAN (1-1208): 0: 794: 100.00		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		294695 RECQ4_HUMAN (1-1208): 0: 794: 100.00		MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60
+	Hs
		295083 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PRG4_HUMAN (775-1650): 2.91e-14: 81.1: 12.40
+	Hs
		295460 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		134074 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		134116 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		134254 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		571636 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		801879 RECQ1_HUMAN (446-985): 7.98e-133: 422: 24.39		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		134264 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		134175 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		295531 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		1050599 WRN_HUMAN (465-856): 8.98e-111: 381: 29.28		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		1271630 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		571557 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78