HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1208 Hs			1 504
+	Hs
		196928 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PRP4_HUMAN (308-504): 2.63e-48: 176: 18.84
+	Hs
		294619 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		294989 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5B_HUMAN (89-333): 1.53e-40: 150: 16.60
+	Hs
		867626 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		801949 RECQ1_HUMAN (446-985): 7.98e-133: 422: 24.39		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		134154 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		867630 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		1271615 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		181721 DDX3Y_HUMAN (305-843): 2.04e-126: 405: 15.09		POC1A_HUMAN (88-377): 5.18e-64: 215: 20.68
+	Hs
		1288310 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		295548 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		867652 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		1271621 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		1050616 WRN_HUMAN (465-856): 8.98e-111: 381: 29.28		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		133956 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1333547 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		295566 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		903507 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		903410 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1271679 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86