HitPredict

Interactor 1: RECQ5 (O94762)
ATP-dependent DNA helicase Q5 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ5) (DNA helicase, RecQ-like type 5) (RecQ5) (RecQ protein-like 5)
Gene: RECQL5

Interactor 2: RPR1B (Q9NQG5)
Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)
Gene: RPRD1B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000993 - RNA polymerase II complex binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0097550 - transcription preinitiation complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 991 Hs			1 326
+	Hs
		295551 RECQ5_HUMAN (1-991): 0: 730: 100.00		RPR1A_HUMAN (1-326): 1.47e-93: 282: 65.34
+	Hs
		295533 RECQ5_HUMAN (1-991): 0: 730: 100.00		RPRD2_HUMAN (9-322): 2.87e-73: 247: 25.00
+	Hs
		295478 RECQ5_HUMAN (1-991): 0: 730: 100.00		SCAF4_HUMAN (8-187): 2.45e-36: 140: 17.46
+	Hs
		801897 RECQ1_HUMAN (10-443): 0: 581: 36.53		RPRD2_HUMAN (9-322): 2.87e-73: 247: 25.00
+	Hs
		295289 RECQ4_HUMAN (8-369): 1.31e-112: 377: 33.59		RPR1B_HUMAN (1-326): 6.99e-94: 283: 100.00
+	Hs
		295145 RECQ4_HUMAN (8-369): 1.31e-112: 377: 33.59		RPR1A_HUMAN (1-326): 1.47e-93: 282: 65.34
+	Hs
		300407 IF4A3_HUMAN (9-392): 5.34e-121: 377: 15.01		PCF11_HUMAN (9-227): 5.39e-41: 154: 18.30
+	Sp
		624021 DBP2_SCHPO (3-392): 8.33e-126: 395: 18.86		SEB1_SCHPO (1-206): 1.58e-33: 132: 14.41