Protein: EPHB3
Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)

Gene: EPHB3
Organism: Homo sapiens
Interactions: 29
UniProt ID: P54753

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001655 - urogenital system development
GO:0005003 - ephrin receptor activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

914386

EFNB2
Ephrin-B2

4

20

High-throughput

0.892

High

931807

EFNB1
Ephrin-B1

2

20

High-throughput

0.776

High

931806

AFAD
Afadin

1

20

Small-scale

0.740

High

635699

RASA1
Ras GTPase-activating protein 1

1

20

Small-scale

0.724

High

440460

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.647

High

855564

CRK
Adapter molecule crk

1

20

Small-scale

0.647

High

931810

EFNB3
Ephrin-B3

1

20

Small-scale

0.647

High

710797

EPHB2
Ephrin type-B receptor 2

1

18

High-throughput

0.646

High

931814

AGRG5
Adhesion G-protein coupled receptor G5

2

8

High-throughput

0.628

High

410732

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

463418

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

761195

RYK
Tyrosine-protein kinase RYK

1

20

Small-scale

0.618

High

931809

SRC8
Src substrate cortactin

1

20

Small-scale

0.618

High

269162

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

931816

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.579

High

931817

HAVR2
Hepatitis A virus cellular receptor 2

1

2

High-throughput

0.575

High

789617

HPCL1
Hippocalcin-like protein 1

2

1

High-throughput

0.553

High

931813

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

931808

GLGB
1,4-alpha-glucan-branching enzyme

1

5

High-throughput

0.541

High

931820

RN186
E3 ubiquitin-protein ligase RNF186

1

1

Small-scale

0.535

High

931822

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

931811

NFRKB
Nuclear factor related to kappa-B-binding protein

1

5

High-throughput

0.494

High

603905

CXA1
Gap junction alpha-1 protein

1

12

High-throughput

0.479

High

931815

CXD3
Gap junction delta-3 protein

1

12

High-throughput

0.479

High

254904

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

12

High-throughput

0.445

High

931812

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.445

High

931821

FBX2
F-box only protein 2

1

6

High-throughput

0.445

High

931819

MF14A
Hippocampus abundant transcript 1 protein

1

7

High-throughput

0.407

High

931818

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025