HitPredict

Interactor 1: ACL6B (O94805)
Actin-like protein 6B (53 kDa BRG1-associated factor B) (Actin-related protein Baf53b) (ArpNalpha) (BRG1-associated factor 53B) (BAF53B)
Gene: ACTL6B

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29028833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~HSA, Actin~SNF2-rel_dom
Common GO terms	GO:0003682 - chromatin binding GO:0035267 - NuA4 histone acetyltransferase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 3159
+	Hs
		331576 ACL6A_HUMAN (1-426): 0: 777: 83.92		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		891979 ACTB_HUMAN (9-425): 0: 549: 35.49		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		929972 ACTG_HUMAN (9-425): 0: 549: 35.49		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		331614 ACL6A_HUMAN (1-426): 0: 777: 83.92		INO80_HUMAN (1754-2150): 2.56e-83: 307: 25.38
+	Mm
		1150293 ACL6B_MOUSE (1-426): 0: 893: 99.77		SMCA2_MOUSE (2682-2984): 5.95e-09: 64.5: 13.03
+	Mm
		1111963 ACL6B_MOUSE (1-426): 0: 893: 99.77		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		331590 ACL6A_HUMAN (1-426): 0: 777: 83.92		SMRCD_HUMAN (1895-2052): 1.85e-24: 115: 38.27
+	Hs
		296494 ACL6B_HUMAN (1-426): 0: 584: 100.00		INO80_HUMAN (1754-2150): 2.56e-83: 307: 25.38
+	Hs
		892104 ACTB_HUMAN (9-425): 0: 549: 35.49		INO80_HUMAN (1754-2150): 2.56e-83: 307: 25.38
+	Mm
		1208490 ACL6A_MOUSE (1-426): 0: 774: 83.92		EP400_MOUSE (2511-3159): 1.94e-10: 69.5: 10.79
+	Hs
		331473 ACL6A_HUMAN (1-426): 0: 777: 83.92		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		331474 ACL6A_HUMAN (1-426): 0: 777: 83.92		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Mm
		1150300 ACL6A_MOUSE (1-426): 0: 774: 83.92		SMCA2_MOUSE (2682-2984): 5.95e-09: 64.5: 13.03
+	Mm
		1111976 ACL6A_MOUSE (1-426): 0: 774: 83.92		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		296435 ACL6B_HUMAN (1-426): 0: 584: 100.00		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		891853 ACTB_HUMAN (9-425): 0: 549: 35.49		SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39
+	Hs
		929905 ACTG_HUMAN (9-425): 0: 549: 35.49		SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39
+	Xl
		292752 ACTB_XENLA (9-425): 0: 549: 35.49		Q4VQ79_XENLA (2756-3006): 7.42e-09: 64.1: 13.13
+	Hs
		846910 ACTB_HUMAN (9-425): 0: 549: 35.49		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		846917 ACTG_HUMAN (9-425): 0: 549: 35.49		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17