Protein: AP4S1
AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin)

Gene: AP4S1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q9Y587

Gene Ontology (top 5):
GO:0005802 - trans-Golgi network
GO:0006605 - protein targeting
GO:0008104 - intracellular protein localization
GO:0015031 - protein transport
GO:0016192 - vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462474

AP4E1
AP-4 complex subunit epsilon-1

3

20

Small-scale

0.863

High

1491506

AP4B1
AP-4 complex subunit beta-1

2

20

High-throughput

0.811

High

125862

AP4M1
AP-4 complex subunit mu-1

1

19

High-throughput

0.691

High

1398745

AP4AT
AP-4 complex accessory subunit Tepsin

3

1

Small-scale

0.662

High

905340

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.536

High

423531

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

390263

FETA
Alpha-fetoprotein

1

1

High-throughput

0.494

High

895226

5HT6R
5-hydroxytryptamine receptor 6

1

1

High-throughput

0.494

High

136567

GOLI4
Golgi integral membrane protein 4

1

2

High-throughput

0.489

High

624688

SL9A1
Sodium/hydrogen exchanger 1

1

3

High-throughput

0.489

High

1127783

HLTF
Helicase-like transcription factor

1

1

High-throughput

0.489

High

1412373

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

1

High-throughput

0.489

High

1448596

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.489

High

219012

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

1276387

ATG9A
Autophagy-related protein 9A

1

6

High-throughput

0.479

High

988066

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.464

High

541783

FGFR1
Fibroblast growth factor receptor 1

1

8

High-throughput

0.437

High

694100

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.437

High

947326

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.437

High

107411

F8W7C6
Ribosomal protein L10

1

1

High-throughput

0.407

High

1434608

SUV92
Histone-lysine N-methyltransferase SUV39H2

2

0

High-throughput

0.328

High

1006002

GTF2I
General transcription factor II-I

1

0

High-throughput

0.282

High

1405593

TEAD3
Transcriptional enhancer factor TEF-5

1

0

High-throughput

0.282

High

837921

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.279

Low

1083165

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

1240732

CDC73
Parafibromin

1

0

High-throughput

0.279

Low

1310560

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1366012

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.279

Low

245377

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025