HitPredict

Interactor 1: KPCD3 (O94806)
Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)
Gene: PRKD3

Interactor 2: KPCD1 (Q15139)
Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
Gene: PRKD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 33961781, 35271311, 32707033
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PH, C1_1~Pkinase, PH~PH, PH~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 6 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 890
Hs

1 912
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Last updated: 15 Jul 2024