HitPredict

Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Interactor 2: ANR12 (Q6UB98)
Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein)
Gene: ANKRD12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1529 Hs			1 2062
+	Hs
		296660 SLIT2_HUMAN (1-1529): 0: 926: 100.00		Q6PG48_HUMAN (1-291): 1.82e-66: 230: 100.00
+	Hs
		804293 NOTC1_HUMAN (1249-1526): 7.72e-37: 154: 19.64		ANR44_HUMAN (15-316): 5.29e-58: 221: 17.10
+	Hs
		1237561 NOTC3_HUMAN (1124-1529): 7.25e-32: 138: 16.67		ANR44_HUMAN (15-316): 5.29e-58: 221: 17.10
+	Hs
		167042 NOTC3_HUMAN (1124-1529): 7.25e-32: 138: 16.67		ANR28_HUMAN (28-272): 3.62e-49: 194: 14.39
+	Hs
		980449 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		ANR44_HUMAN (15-316): 5.29e-58: 221: 17.10
+	Hs
		166914 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		ANR28_HUMAN (28-272): 3.62e-49: 194: 14.39
+	Dm
		65546 NOTCH_DROME (1255-1524): 2.55e-36: 153: 18.03		A8JNM5_DROME (184-327): 2.65e-25: 118: 24.31
+	Hs
		1167037 FAT4_HUMAN (847-957): 7.03e-10: 66.3: 20.72		TNKS2_HUMAN (155-524): 2.65e-47: 188: 15.42
+	Hs
		63587 NOTC2_HUMAN (859-1092): 1.06e-16: 88.7: 21.90		ASB14_HUMAN (179-274): 2.51e-09: 64.3: 37.50