Protein: AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1)

Gene: AL1L1, ALDH1L1
Organism: Homo sapiens
Interactions: 42
UniProt ID: O75891

Gene Ontology (top 5):
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006740 - NADPH regeneration
GO:0009058 - biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296663

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

2

14

High-throughput

0.789

High

296678

DAPLE
Protein Daple

2

2

High-throughput

0.574

High

296681

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.561

High

296670

APBP2
Amyloid protein-binding protein 2

2

5

High-throughput

0.553

High

296650

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

296653

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

5

High-throughput

0.536

High

296659

DCAF7
DDB1- and CUL4-associated factor 7

1

7

High-throughput

0.536

High

296667

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

104971

APRIO
Alternative prion protein

2

3

High-throughput

0.533

High

296665

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

296673

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

0

High-throughput

0.513

High

137888

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

Small-scale

0.479

High

296649

HS90A
Heat shock protein HSP 90-alpha

1

7

Small-scale

0.479

High

296651

ENPL
Endoplasmin

1

7

Small-scale

0.479

High

296652

PRS6A
26S proteasome regulatory subunit 6A

1

12

Small-scale

0.479

High

296654

PRS7
26S proteasome regulatory subunit 7

1

2

Small-scale

0.479

High

296655

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

296656

PRS6B
26S proteasome regulatory subunit 6B

1

2

Small-scale

0.479

High

296657

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

Small-scale

0.479

High

296660

PRS4
26S proteasome regulatory subunit 4

1

2

Small-scale

0.479

High

296661

PRS8
26S proteasome regulatory subunit 8

1

3

Small-scale

0.479

High

296662

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

296669

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

Small-scale

0.479

High

296671

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

5

Small-scale

0.479

High

296672

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

Small-scale

0.479

High

296675

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

4

Small-scale

0.479

High

296676

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

Small-scale

0.479

High

296679

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

296680

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

296646

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.470

High

128113

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

Small-scale

0.458

High

296668

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

296682

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

7

High-throughput

0.445

High

296674

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.437

High

183559

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.426

High

296648

PRIO
Major prion protein

1

0

High-throughput

0.426

High

296645

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.407

High

296647

C1QC
Complement C1q subcomponent subunit C

1

4

High-throughput

0.407

High

296677

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

1

High-throughput

0.407

High

296664

CC062
Uncharacterized protein C3orf62

1

0

High-throughput

0.279

Low

296666

F90A1
Protein FAM90A1

1

0

High-throughput

0.279

Low

296658

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025