HitPredict

Interactor 1: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2

Interactor 2: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	32296183, 33961781, 34133714, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 416
+	Hs
		297891 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		KRT37_HUMAN (17-409): 1.92e-148: 430: 60.91
+	Hs
		298007 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		K1C40_HUMAN (6-385): 2.33e-143: 416: 62.69
+	Hs
		297898 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		K2C75_HUMAN (19-381): 5.07e-95: 297: 26.58
+	Hs
		297889 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		KRT34_HUMAN (1-391): 2.98e-95: 292: 89.00
+	Hs
		297937 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		K1C20_HUMAN (52-364): 9.94e-95: 292: 50.48
+	Hs
		298043 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		KRT35_HUMAN (2-412): 4.84e-87: 273: 69.83
+	Hs
		297890 SPF27_HUMAN (1-225): 9.41e-103: 298: 100.00		KRT36_HUMAN (4-400): 1.13e-81: 260: 69.65