HitPredict

Interactor 1: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30344098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005925 - focal adhesion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1100 Hs			1 323
+	Hs
		298966 SRBS2_HUMAN (1-1100): 0: 744: 100.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Mm
		906255 SRBS2_MOUSE (1-1100): 0: 711: 86.74		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Mm
		561155 SPTN1_MOUSE (86-954): 3.26e-63: 238: 12.30		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Hs
		738090 ITSN2_HUMAN (345-1100): 1.94e-53: 207: 13.12		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		906448 SPTN1_HUMAN (86-954): 3.53e-63: 238: 11.98		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		737723 GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		737776 MYO1E_HUMAN (874-1100): 1.36e-21: 103: 16.00		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		905820 GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		737939 SH3R2_HUMAN (868-995): 7.62e-13: 74.7: 35.82		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		906402 GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Mm
		906650 GRB2_MOUSE (743-923): 9.08e-28: 114: 18.42		PP1B_MOUSE (1-322): 0: 560: 86.89
+	Hs
		906434 MYO1E_HUMAN (874-1100): 1.36e-21: 103: 16.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		906037 SH3R2_HUMAN (868-995): 7.62e-13: 74.7: 35.82		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		906455 SRC8_HUMAN (918-1099): 3.51e-17: 88.5: 14.84		PP1B_HUMAN (1-322): 0: 560: 86.89