Protein: MANS1
MANSC domain-containing protein 1 (Loss of heterozygosity 12 chromosomal region 3 protein)

Gene: MANS1, MANSC1
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9H8J5

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

273582

DJC13
DnaJ homolog subfamily C member 13

2

2

High-throughput

0.628

High

787247

BMR1A
Bone morphogenetic protein receptor type-1A

2

2

High-throughput

0.628

High

1039001

NUCB1
Nucleobindin-1

2

1

High-throughput

0.628

High

1278322

LRP10
Low-density lipoprotein receptor-related protein 10

2

1

High-throughput

0.628

High

1334567

RN149
E3 ubiquitin-protein ligase RNF149

2

2

High-throughput

0.628

High

62161

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

0

High-throughput

0.602

High

140441

SDCB1
Syntenin-1

2

0

High-throughput

0.602

High

161344

P5I11
Tumor protein p53-inducible protein 11

2

0

High-throughput

0.602

High

290266

TM1L1
TOM1-like protein 1

2

0

High-throughput

0.602

High

331804

MTMR5
Myotubularin-related protein 5

2

0

High-throughput

0.602

High

387464

APOE
Apolipoprotein E

2

0

High-throughput

0.602

High

775778

ATP7B
Copper-transporting ATPase 2

2

0

High-throughput

0.602

High

846792

GRK6
G protein-coupled receptor kinase 6

2

0

High-throughput

0.602

High

907844

CLCN7
H(+)/Cl(-) exchange transporter 7

2

0

High-throughput

0.602

High

999685

HBA
Hemoglobin subunit alpha

2

0

High-throughput

0.602

High

1022649

LRP2
Low-density lipoprotein receptor-related protein 2

2

0

High-throughput

0.602

High

1097891

STX5
Syntaxin-5

2

0

High-throughput

0.602

High

1130720

DIP2A
Disco-interacting protein 2 homolog A

2

0

High-throughput

0.602

High

1139033

SNX17
Sorting nexin-17

2

0

High-throughput

0.602

High

1154750

VAMP3
Vesicle-associated membrane protein 3

2

0

High-throughput

0.602

High

1206345

WDR44
WD repeat-containing protein 44

2

0

High-throughput

0.602

High

1243050

PKN3
Serine/threonine-protein kinase N3

2

0

High-throughput

0.602

High

1338632

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

2

0

High-throughput

0.602

High

1349728

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

2

0

High-throughput

0.602

High

1357833

S35F5
Solute carrier family 35 member F5

2

0

High-throughput

0.602

High

1413157

NFIP1
NEDD4 family-interacting protein 1

2

0

High-throughput

0.602

High

1417150

S12A9
Solute carrier family 12 member 9

2

0

High-throughput

0.602

High

1436386

PKHB1
Pleckstrin homology domain-containing family B member 1

2

0

High-throughput

0.602

High

1436388

CCPG1
Cell cycle progression protein 1

2

0

High-throughput

0.602

High

1436389

KDIS
Kinase D-interacting substrate of 220 kDa

2

0

High-throughput

0.602

High

136434

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

2

High-throughput

0.574

High

220517

RNF13
E3 ubiquitin-protein ligase RNF13

2

2

High-throughput

0.574

High

298958

DNJB5
DnaJ homolog subfamily B member 5

2

1

High-throughput

0.574

High

522738

PTPRF
Receptor-type tyrosine-protein phosphatase F

2

1

High-throughput

0.574

High

658772

JAK1
Tyrosine-protein kinase JAK1

2

2

High-throughput

0.574

High

839086

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2

1

High-throughput

0.574

High

839178

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

1

High-throughput

0.574

High

931995

EPHB4
Ephrin type-B receptor 4

2

1

High-throughput

0.574

High

1102756

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

1

High-throughput

0.574

High

1346645

VANG1
Vang-like protein 1

2

1

High-throughput

0.574

High

1396679

MARK4
MAP/microtubule affinity-regulating kinase 4

2

2

High-throughput

0.574

High

1436383

DNJB9
DnaJ homolog subfamily B member 9

2

2

High-throughput

0.574

High

1436384

DNJB4
DnaJ homolog subfamily B member 4

2

1

High-throughput

0.574

High

1436390

VANG2
Vang-like protein 2

2

1

High-throughput

0.574

High

541688

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.536

High

1009889

NUCB2
Nucleobindin-2

1

1

High-throughput

0.536

High

1270526

MARK2
Serine/threonine-protein kinase MARK2

1

2

High-throughput

0.536

High

1294262

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.536

High

1436392

NISCH
Nischarin

1

1

High-throughput

0.536

High

180053

BET1
BET1 homolog

1

0

High-throughput

0.513

High

213340

ADCY6
Adenylate cyclase type 6

1

0

High-throughput

0.513

High

1034067

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.513

High

1316821

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

0

High-throughput

0.513

High

1436381

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.513

High

1436385

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.513

High

348205

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

3

High-throughput

0.489

High

692135

MARK3
MAP/microtubule affinity-regulating kinase 3

1

2

High-throughput

0.489

High

787343

ACV1B
Activin receptor type-1B

1

2

High-throughput

0.489

High

1063015

DDR1
Epithelial discoidin domain-containing receptor 1

1

2

High-throughput

0.489

High

1116841

AVR2B
Activin receptor type-2B

1

2

High-throughput

0.489

High

1147434

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.489

High

1364879

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.489

High

1406211

OSMR
Oncostatin-M-specific receptor subunit beta

1

2

High-throughput

0.489

High

548611

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.458

High

373169

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406654

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

604211

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.426

High

65363

TCAF2
TRPM8 channel-associated factor 2

2

0

High-throughput

0.328

High

249667

SNX3
Sorting nexin-3

2

0

High-throughput

0.328

High

252721

TSN3
Tetraspanin-3

2

0

High-throughput

0.328

High

325408

DIRA1
GTP-binding protein Di-Ras1

2

0

High-throughput

0.328

High

876281

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

2

0

High-throughput

0.328

High

1025637

CDK17
Cyclin-dependent kinase 17

2

0

High-throughput

0.328

High

1133231

STAR3
StAR-related lipid transfer protein 3

2

0

High-throughput

0.328

High

1138999

TRAM2
Translocating chain-associated membrane protein 2

2

0

High-throughput

0.328

High

1228779

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.328

High

1242496

NFRKB
Nuclear factor related to kappa-B-binding protein

2

0

High-throughput

0.328

High

1280667

PKHH3
Pleckstrin homology domain-containing family H member 3

2

0

High-throughput

0.328

High

1312379

SIR2
NAD-dependent protein deacetylase sirtuin-2

2

0

High-throughput

0.328

High

1327885

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

2

0

High-throughput

0.328

High

1329683

AN13C
Ankyrin repeat domain-containing protein 13C

2

0

High-throughput

0.328

High

1335570

DGLB
Diacylglycerol lipase-beta

2

0

High-throughput

0.328

High

1380409

RNF34
E3 ubiquitin-protein ligase RNF34

2

0

High-throughput

0.328

High

1381821

TR19L
Tumor necrosis factor receptor superfamily member 19L

2

0

High-throughput

0.328

High

1389984

MB12A
Multivesicular body subunit 12A

2

0

High-throughput

0.328

High

1399749

RBM14
RNA-binding protein 14

2

0

High-throughput

0.328

High

1406952

CDC6
Cell division control protein 6 homolog

2

0

High-throughput

0.328

High

1412223

TTYH2
Protein tweety homolog 2

2

0

High-throughput

0.328

High

1416682

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

2

0

High-throughput

0.328

High

1428291

NRSN2
Neurensin-2

2

0

High-throughput

0.328

High

1436382

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

0

High-throughput

0.328

High

1436387

MRM2
rRNA methyltransferase 2, mitochondrial

2

0

High-throughput

0.328

High

1436391

NOTC3
Neurogenic locus notch homolog protein 3

2

0

High-throughput

0.328

High

1249509

VSTM1
V-set and transmembrane domain-containing protein 1

2

0

High-throughput

0.316

High

261279

NSMA
Sphingomyelin phosphodiesterase 2

2

0

High-throughput

0.313

High

557472

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.279

Low

732704

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.279

Low

902076

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.279

Low

1153117

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.279

Low

1352371

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

1392788

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

1407219

ABCA3
Phospholipid-transporting ATPase ABCA3

1

0

High-throughput

0.279

Low

1412069

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.279

Low

1436393

RBGP1
Rab GTPase-activating protein 1

1

0

High-throughput

0.279

Low

1436394

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.279

Low

424556

PAI2
Plasminogen activator inhibitor 2

1

0

High-throughput

0.232

Low

1116456

FHL1
Four and a half LIM domains protein 1

1

0

High-throughput

0.232

Low

1365814

ZN516
Zinc finger protein 516

1

0

High-throughput

0.232

Low

1435642

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025