Interactor 1: UBXN7 (O94888)
UBX domain-containing protein 7
Gene: UBXN7

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 28274878, 29540532, 18775313, 22466964, 26389662, 32296183, 33961781, unassigned1304
Identification Methods x-ray crystallography, pull down, proximity labelling technology, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC48_2~UBX, CDC48_N~UBX
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
GO:0034098 - VCP-NPL4-UFD1 AAA ATPase complex
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 489
Hs

1 806
+ Hs
+ Dm
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+ At
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+ Ce
+ Ce
+ Ce
+ Ce
+ Sc
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+ Mm
+ Ce
+ Ce

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Last updated: 15 Jul 2024