HitPredict

Interactor 1: KLH18 (O94889)
Kelch-like protein 18
Gene: KLHL18

Interactor 2: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 443
+	Hs
		897321 KLHL8_HUMAN (3-572): 6.73e-160: 472: 34.90		CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00
+	Hs
		897262 KLH10_HUMAN (26-573): 1.28e-155: 460: 31.03		CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00
+	Hs
		299514 KLH18_HUMAN (1-574): 9.48e-176: 510: 100.00		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		299532 KLH18_HUMAN (1-574): 9.48e-176: 510: 100.00		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Hs
		1024231 KLHL8_HUMAN (3-572): 6.73e-160: 472: 34.90		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1024172 KLH10_HUMAN (26-573): 1.28e-155: 460: 31.03		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1153792 KLH10_HUMAN (26-573): 1.28e-155: 460: 31.03		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Hs
		897257 KLH12_HUMAN (414-572): 3.15e-33: 135: 27.61		CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00
+	Hs
		897322 KLH13_HUMAN (431-573): 1.06e-27: 119: 25.33		CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00
+	Hs
		897264 KLH24_HUMAN (282-384): 2.26e-10: 65.2: 26.92		CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00
+	Hs
		1024168 KLH12_HUMAN (414-572): 3.15e-33: 135: 27.61		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1024232 KLHL9_HUMAN (431-573): 9.96e-28: 119: 24.67		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1024234 KLH13_HUMAN (431-573): 1.06e-27: 119: 25.33		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1120807 KLH12_HUMAN (414-572): 3.15e-33: 135: 27.61		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Hs
		1311911 KLH13_HUMAN (431-573): 1.06e-27: 119: 25.33		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Hs
		1024184 KLH36_HUMAN (476-574): 4.95e-11: 67.5: 18.69		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		1024173 KLH24_HUMAN (282-384): 2.26e-10: 65.2: 26.92		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02