Protein: KALRN
Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)

Gene: KALRN
Organism: Homo sapiens
Interactions: 50
UniProt ID: O60229

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

238812

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

Small-scale

0.768

High

238834

SNCAP
Synphilin-1

1

20

Small-scale

0.740

High

238790

DSCAM
Cell adhesion molecule DSCAM

1

9

High-throughput

0.698

High

238819

GFI1B
Zinc finger protein Gfi-1b

1

2

High-throughput

0.656

High

238804

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

1

Small-scale

0.647

High

238815

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

19

Small-scale

0.621

High

238823

LNX1
E3 ubiquitin-protein ligase LNX

1

13

Small-scale

0.621

High

62862

POTEF
POTE ankyrin domain family member F

1

20

High-throughput

0.618

High

230483

KIF1C
Kinesin-like protein KIF1C

1

10

High-throughput

0.618

High

238795

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.618

High

238796

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

238800

RAB4A
Ras-related protein Rab-4A

1

12

High-throughput

0.618

High

238807

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.618

High

238818

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

17

Small-scale

0.618

High

238820

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

238833

RAB21
Ras-related protein Rab-21

1

15

High-throughput

0.618

High

238828

NDEL1
Nuclear distribution protein nudE-like 1

2

20

High-throughput

0.590

High

238830

DISC1
Disrupted in schizophrenia 1 protein

2

10

High-throughput

0.590

High

238827

CDC5L
Cell division cycle 5-like protein

2

8

High-throughput

0.576

High

238797

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.575

High

238821

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

7

High-throughput

0.575

High

238826

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

13

High-throughput

0.575

High

238793

PCNT
Pericentrin

1

20

High-throughput

0.541

High

238798

ENOB
Beta-enolase

1

3

High-throughput

0.541

High

238803

GRIK1
Glutamate receptor ionotropic, kainate 1

1

13

High-throughput

0.541

High

238805

NRIP1
Nuclear receptor-interacting protein 1

1

5

High-throughput

0.541

High

238817

MORC3
MORC family CW-type zinc finger protein 3

1

2

High-throughput

0.541

High

238791

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

9

High-throughput

0.514

High

139667

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

2

High-throughput

0.508

High

184663

ATX7
Ataxin-7

1

4

High-throughput

0.508

High

238802

COIL
Coilin

1

1

High-throughput

0.508

High

238799

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

1

Small-scale

0.481

High

238824

DTBP1
Dysbindin

1

2

High-throughput

0.481

High

238792

SF3B1
Splicing factor 3B subunit 1

1

6

High-throughput

0.479

High

238801

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

238806

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

238808

HAP1
Huntingtin-associated protein 1

1

17

Small-scale

0.479

High

238811

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

8

Small-scale

0.479

High

238814

CUL4A
Cullin-4A

1

16

High-throughput

0.479

High

238822

CE112
Centrosomal protein of 112 kDa

1

20

High-throughput

0.479

High

238829

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

14

Small-scale

0.479

High

238832

HDAC6
Protein deacetylase HDAC6

1

14

Small-scale

0.479

High

238810

STXB1
Syntaxin-binding protein 1

1

5

High-throughput

0.457

High

238813

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.457

High

238825

SPTCS
Spatacsin

1

2

Small-scale

0.457

High

238794

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.445

High

238816

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

126923

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

238809

DSCR9
Down syndrome critical region protein 9

1

4

High-throughput

0.417

High

238831

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025