HitPredict

Interactor 1: GLSK (O94925)
Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
Gene: GLS

Interactor 2: GLSL (Q9UI32)
Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)
Gene: GLS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~EF-hand_14, Ank_2~Glutaminase, EF-hand_14~EF-hand_14, EF-hand_14~Glutaminase, Glutaminase~Glutaminase
Common GO terms GO:0004359 - glutaminase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006537 - glutamate biosynthetic process
GO:0006543 - glutamine catabolic process
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 669
Hs

1 602
+ Hs
+ Mm
+ Rn
+ Mm
+ Dm
+ Hs
+ Mm
+ Dr
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024