HitPredict

Interactor 1: GLSK (O94925)
Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) (K-glutaminase) (L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
Gene: GLS

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	38496616
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 648
+	Hs
		374141 ANK3_HUMAN (488-666): 4.57e-33: 139: 15.64		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374070 ANK2_HUMAN (540-669): 2.52e-25: 114: 21.54		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373957 RIPK4_HUMAN (543-669): 1.7e-15: 82.4: 15.75		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374864 Q9H4D1_HUMAN (543-669): 1.6e-15: 82.4: 15.75		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373840 CDN2C_HUMAN (557-645): 4.82e-13: 69.3: 20.66		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Mm
		93731 E9Q9B7_MOUSE (455-623): 8.38e-16: 83.9: 14.04		BRAF_MOUSE (38-647): 3.22e-169: 503: 55.52
+	Hs
		488633 RIPK4_HUMAN (543-669): 1.7e-15: 82.4: 15.75		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		488803 Q9H4D1_HUMAN (543-669): 1.6e-15: 82.4: 15.75		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		412433 MYO16_HUMAN (342-669): 1.58e-52: 198: 15.84		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		433392 ANR12_HUMAN (537-643): 7.48e-30: 128: 22.43		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		412234 ANR12_HUMAN (537-643): 7.48e-30: 128: 22.43		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		523028 ANR54_HUMAN (535-644): 2.92e-27: 114: 25.89		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		433389 ANR54_HUMAN (535-644): 2.92e-27: 114: 25.89		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Zm
		77269 B4FUM8_MAIZE (523-637): 2.24e-21: 92.8: 21.74		C0PDS7_MAIZE (273-627): 1.77e-103: 338: 29.41
+	Hs
		1217986 Q9H4D1_HUMAN (543-669): 1.6e-15: 82.4: 15.75		KSR1_HUMAN (138-648): 6.15e-108: 348: 24.61
+	Hs
		883556 RIPK4_HUMAN (543-669): 1.7e-15: 82.4: 15.75		KSR1_HUMAN (138-648): 6.15e-108: 348: 24.61