Interactor 1: PDE5A (O76074)
cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)
Gene: PDE5A

Interactor 2: ITPR1 (Q14643)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5 trisphosphate receptor) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Gene: ITPR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.50 0.457

The method score is based on:

Property Details
Experiments 18757735
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms -
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 875
Hs

1 2758
+ Hs
+ Mm
+ Rn

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Last updated: 11Aug2025