HitPredict

Interactor 1: NXPH2 (O95156)
Neurexophilin-2
Gene: NXPH2

Interactor 2: CELR1 (Q9NYQ6)
Cadherin EGF LAG seven-pass G-type receptor 1 (Cadherin family member 9) (Flamingo homolog 2) (hFmi2)
Gene: CELSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Laminin_G_2~Neurexophilin
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 264 Hs			1 3014
+	Hs
		305284 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		CELR1_HUMAN (25-3014): 0: 2226: 100.00
+	Hs
		305229 NXPH2_HUMAN (1-264): 0: 520: 100.00		PCDH9_HUMAN (222-786): 2.77e-130: 446: 28.33
+	Hs
		305230 NXPH2_HUMAN (1-264): 0: 520: 100.00		CELR2_HUMAN (1-557): 3.48e-96: 351: 20.11
+	Hs
		305215 NXPH2_HUMAN (1-264): 0: 520: 100.00		PCDH1_HUMAN (244-783): 1.44e-58: 224: 31.69
+	Hs
		305283 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		CELR2_HUMAN (1-557): 3.48e-96: 351: 20.11
+	Hs
		305319 NXPH4_HUMAN (96-261): 2.72e-90: 271: 49.54		PCDB3_HUMAN (1-557): 1.05e-99: 343: 17.80
+	Hs
		305216 NXPH2_HUMAN (1-264): 0: 520: 100.00		FAT1_HUMAN (2035-2185): 6.71e-16: 87.3: 10.63
+	Hs
		305221 NXPH2_HUMAN (1-264): 0: 520: 100.00		FAT4_HUMAN (2019-2154): 7.82e-14: 80.8: 13.48
+	Hs
		885685 NXPH1_HUMAN (76-264): 5.26e-128: 365: 80.95		PCDH1_HUMAN (244-783): 1.44e-58: 224: 31.69
+	Hs
		305254 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		PCDH1_HUMAN (244-783): 1.44e-58: 224: 31.69