Interactor 1: TRMB (O77263)
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA methylguanosine methyltransferase 1) (tRNA(m7G46)-methyltransferase)
Gene: Mettl1

Interactor 2: WUHO (Q9W415)
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho (protein wuho)
Gene: WUHO

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 38944040, 39317727
Identification Methods anti tag coimmunoprecipitation, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Methyltransf_4~WD40
Common GO terms GO:0005634 - nucleus
GO:0006400 - tRNA modification
GO:0043527 - tRNA methyltransferase complex
GO:0106143 - tRNA (m7G46) methyltransferase complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 256
Dm

1 424
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025