Protein: WDR4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein Wuho homolog) (hWH) (WD repeat-containing protein 4)

Gene: WDR4
Organism: Homo sapiens
Interactions: 46
UniProt ID: P57081

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005829 - cytosol
GO:0006400 - tRNA modification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

944167

TRMB
tRNA

12

2

Small-scale

0.981

High

944145

RS16
Small ribosomal subunit protein uS9

1

10

Small-scale

0.691

High

944146

H4
Histone H4

1

7

Small-scale

0.691

High

944153

CAPS2
Calcium-dependent secretion activator 2

1

0

High-throughput

0.663

High

921526

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

0

High-throughput

0.646

High

823876

PBX2
Pre-B-cell leukemia transcription factor 2

2

4

High-throughput

0.628

High

944156

RN138
E3 ubiquitin-protein ligase RNF138

2

12

High-throughput

0.628

High

944158

RBM14
RNA-binding protein 14

2

19

High-throughput

0.628

High

944164

XPP1
Xaa-Pro aminopeptidase 1

2

5

High-throughput

0.628

High

418908

H2A1B
Histone H2A type 1-B/E

1

9

Small-scale

0.618

High

754776

H2B1B
Histone H2B type 1-B

1

12

Small-scale

0.618

High

915934

NUP98
Nuclear pore complex protein Nup98-Nup96

1

7

High-throughput

0.618

High

944165

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

16

High-throughput

0.618

High

814498

FEN1
Flap endonuclease 1

1

1

Small-scale

0.604

High

944148

TCAL1
Transcription elongation factor A protein-like 1

2

0

High-throughput

0.602

High

944163

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

4

Small-scale

0.578

High

550945

PCNA
Proliferating cell nuclear antigen

1

4

Small-scale

0.554

High

944152

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

944161

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.553

High

928396

TERF1
Telomeric repeat-binding factor 1

1

4

High-throughput

0.552

High

944150

TERF2
Telomeric repeat-binding factor 2

1

4

High-throughput

0.552

High

253241

REV3L
DNA polymerase zeta catalytic subunit

1

4

High-throughput

0.541

High

685143

PAX6
Paired box protein Pax-6

1

6

High-throughput

0.541

High

866628

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.541

High

944147

UBE3A
Ubiquitin-protein ligase E3A

1

14

High-throughput

0.541

High

944149

SF3B4
Splicing factor 3B subunit 4

1

14

High-throughput

0.541

High

944157

CSN5
COP9 signalosome complex subunit 5

1

11

High-throughput

0.541

High

944170

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

20

High-throughput

0.541

High

944171

MRCKB
Serine/threonine-protein kinase MRCK beta

1

10

High-throughput

0.541

High

944154

CARM1
Histone-arginine methyltransferase CARM1

1

8

High-throughput

0.536

High

903050

ZNF84
Zinc finger protein 84

1

0

High-throughput

0.518

High

944159

CENPO
Centromere protein O

1

0

High-throughput

0.513

High

380274

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.494

High

944169

AT7L1
Ataxin-7-like protein 1

1

14

High-throughput

0.489

High

241230

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

272020

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.479

High

320650

UBXN7
UBX domain-containing protein 7

1

3

High-throughput

0.479

High

588334

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

695064

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

767823

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

944151

DPP8
Dipeptidyl peptidase 8

1

1

High-throughput

0.479

High

944155

SIR6
NAD-dependent protein deacylase sirtuin-6

1

11

High-throughput

0.479

High

944168

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

944162

EIF2A
Eukaryotic translation initiation factor 2A

1

17

Small-scale

0.437

High

944166

F118A
Protein FAM118A

4

0

High-throughput

0.364

High

944160

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

2

0

High-throughput

0.328

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025