HitPredict

Interactor 1: RELN (P78509)
Reelin (EC 3.4.21.-)
Gene: RELN

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.747

The method score is based on:

Property Details
Experiments 12899622, 12670700, 17548821, 28123028, 21844191, 23951306, 28446613, 10571240
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0021517 - ventral spinal cord development
GO:0021819 - layer formation in cerebral cortex
and 7 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 3460
Hs

1 963
+ Hs
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024