HitPredict

Interactor 1: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25754235, 23956138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1038 Hs			1 1210
+	Hs
		178088 IPO8_HUMAN (1-1032): 0: 822: 64.41		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338188 XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338800 TNPO1_HUMAN (12-892): 7.7e-134: 428: 13.08		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		155507 TNPO2_HUMAN (12-903): 3.4e-128: 413: 12.41		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		339100 IPO11_HUMAN (1-954): 8.02e-127: 412: 15.94		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		127154 IPO5_HUMAN (4-955): 1.57e-121: 400: 11.44		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338858 IPO9_HUMAN (4-996): 5e-121: 398: 15.05		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338445 IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		383912 TNPO1_HUMAN (12-892): 7.7e-134: 428: 13.08		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		383812 IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Mm
		796521 XPO2_MOUSE (2-921): 2.52e-168: 521: 17.39		ZAP70_MOUSE (718-961): 2.03e-52: 197: 40.00
+	Hs
		435716 TNPO1_HUMAN (12-892): 7.7e-134: 428: 13.08		IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47