HitPredict

Interactor 1: ARI2 (O95376)
E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)
Gene: ARIH2

Interactor 2: ASB9 (Q96DX5)
Ankyrin repeat and SOCS box protein 9 (ASB-9)
Gene: ASB9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 493 Hs			1 294
+	Hs
		312683 ARI2_HUMAN (1-493): 0: 546: 100.00		ASB3_HUMAN (37-219): 1.2e-20: 93.6: 31.25
+	Hs
		228204 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ASB13_HUMAN (37-293): 3.65e-75: 232: 42.25
+	Hs
		228321 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ASB9_HUMAN (1-294): 2.26e-73: 228: 100.00
+	Hs
		227310 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ANK3_HUMAN (173-291): 4e-31: 124: 13.12
+	Hs
		228701 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ASB7_HUMAN (121-284): 1.03e-22: 97.2: 20.47
+	Hs
		229176 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ASB3_HUMAN (37-219): 1.2e-20: 93.6: 31.25
+	Hs
		227985 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ANKH1_HUMAN (192-294): 4.14e-20: 92.5: 14.15
+	Hs
		228417 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		ASB2_HUMAN (72-254): 4e-10: 62.4: 28.34