HitPredict

Interactor 1: GDF11 (O95390)
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)
Gene: GDF11

Interactor 2: AVR2B (Q13705)
Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)
Gene: ACVR2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 33961781, 21054789
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0007498 - mesoderm development
GO:0032924 - activin receptor signaling pathway
GO:0032991 - protein-containing complex
GO:0060021 - roof of mouth development
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 407
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024