Interactor 1: RPGF3 (O95398)
Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)
Gene: RAPGEF3

Interactor 2: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 29513927
Identification Methods pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding
Common GO terms GO:0005886 - plasma membrane
GO:0035556 - intracellular signal transduction
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 923
Hs

1 1430
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024