Protein: SYN1
Synapsin-1 (Brain protein 4.1) (Synapsin I)

Gene: SYN1
Organism: Homo sapiens
Interactions: 48
UniProt ID: P17600

Gene Ontology (top 5):
GO:0000795 - synaptonemal complex
GO:0003779 - actin binding
GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605504

SYN1
Synapsin-1

2

13

Small-scale

0.800

High

605526

SYN2
Synapsin-2

1

8

Small-scale

0.740

High

605520

DGUOK
Deoxyguanosine kinase, mitochondrial

3

1

High-throughput

0.667

High

605531

KTU
Protein kintoun

3

4

High-throughput

0.667

High

605535

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.638

High

605507

SYUA
Alpha-synuclein

3

4

Small-scale

0.625

High

124223

HAX1
HCLS1-associated protein X-1

3

2

High-throughput

0.609

High

605532

ARMC1
Armadillo repeat-containing protein 1

3

1

High-throughput

0.609

High

529025

TAU
Microtubule-associated protein tau

2

20

Small-scale

0.601

High

605515

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.595

High

362726

EGFR
Epidermal growth factor receptor

2

15

Small-scale

0.565

High

474461

VIME
Vimentin

1

3

High-throughput

0.541

High

605522

RBCC1
RB1-inducible coiled-coil protein 1

1

12

High-throughput

0.541

High

605516

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

605525

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

605534

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.513

High

269739

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

8

Small-scale

0.512

High

540800

ERG
Transcriptional regulator ERG

1

20

Small-scale

0.512

High

605527

KAT5
Histone acetyltransferase KAT5

1

4

High-throughput

0.494

High

605510

GPM6A
Neuronal membrane glycoprotein M6-a

1

3

High-throughput

0.489

High

605514

1433E
14-3-3 protein epsilon

1

8

High-throughput

0.489

High

605517

DUSP2
Dual specificity protein phosphatase 2

1

5

High-throughput

0.489

High

605518

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.489

High

605528

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.489

High

605511

BLM
RecQ-like DNA helicase BLM

1

8

Small-scale

0.481

High

605506

NOS1
Nitric oxide synthase 1

1

0

Small-scale

0.480

High

138447

BIN1
Myc box-dependent-interacting protein 1

1

13

Small-scale

0.479

High

240685

PRKN
E3 ubiquitin-protein ligase parkin

1

13

Small-scale

0.479

High

557070

SRC
Proto-oncogene tyrosine-protein kinase Src

1

12

Small-scale

0.479

High

572773

NCF1
Neutrophil cytosol factor 1

1

18

Small-scale

0.479

High

605509

AMPH
Amphiphysin

1

9

Small-scale

0.479

High

605519

DLG2
Disks large homolog 2

1

7

High-throughput

0.479

High

404658

PRIO
Major prion protein

1

3

Small-scale

0.445

High

605512

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

605513

SNP25
Synaptosomal-associated protein 25

1

1

Small-scale

0.445

High

605533

ITSN2
Intersectin-2

1

9

High-throughput

0.439

High

105283

APRIO
Alternative prion protein

1

9

High-throughput

0.437

High

330413

LC7L3
Luc7-like protein 3

1

1

High-throughput

0.437

High

605505

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

Small-scale

0.437

High

605508

CRK
Adapter molecule crk

1

17

Small-scale

0.437

High

605529

SP130
Histone deacetylase complex subunit SAP130

1

10

High-throughput

0.437

High

114493

H0YBV7
LUC7 like 3 pre-mRNA splicing factor

1

1

High-throughput

0.407

High

116433

H7BXF5
Sin3A associated protein 130

1

12

High-throughput

0.407

High

605521

ERI1
3'-5' exoribonuclease 1

1

0

High-throughput

0.279

Low

605523

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.279

Low

605524

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.279

Low

605530

ANTR1
Anthrax toxin receptor 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025