HitPredict

Interactor 1: A0A0S2Z4D7 (A0A0S2Z4D7)
NCK adaptor protein 1 isoform 2 (NCK adaptor protein 1, isoform CRA_b)
Gene: NCK1

Interactor 2: EFS (O43281)
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)
Gene: EFS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Hs			1 561
+	Hs
		199508 BLK_HUMAN (2-169): 6.03e-48: 164: 18.18		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Hs
		199497 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		EFS_HUMAN (1-561): 3.37e-71: 239: 100.00
+	Mm
		639451 LYN_MOUSE (2-169): 7.16e-52: 174: 18.75		EFS_MOUSE (1-561): 2.45e-61: 213: 79.50
+	Hs
		297808 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		K0754_HUMAN (34-464): 4e-33: 137: 13.71
+	Hs
		433761 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		CASL_HUMAN (6-336): 2.64e-31: 131: 24.93
+	Hs
		411721 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		CASL_HUMAN (6-336): 2.64e-31: 131: 24.93
+	Hs
		433891 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MINK1_HUMAN (48-378): 5.94e-26: 115: 14.67
+	Hs
		411790 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		MINK1_HUMAN (48-378): 5.94e-26: 115: 14.67
+	Hs
		442817 HCK_HUMAN (2-169): 1.03e-52: 176: 21.59		ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85
+	Hs
		433721 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		ACK1_HUMAN (9-484): 1.17e-23: 107: 14.85
+	Hs
		433853 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MICA3_HUMAN (61-424): 2.25e-21: 100: 16.45
+	Hs
		203198 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		SYNJ1_HUMAN (95-472): 7.88e-19: 92.8: 13.96
+	Hs
		433560 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MUC1_HUMAN (63-481): 6.08e-16: 83.6: 11.37
+	Hs
		411582 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		MUC1_HUMAN (63-481): 6.08e-16: 83.6: 11.37
+	Hs
		442799 HCK_HUMAN (2-169): 1.03e-52: 176: 21.59		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Hs
		433668 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Mm
		639448 LYN_MOUSE (2-169): 7.16e-52: 174: 18.75		BCAR1_MOUSE (7-431): 8.12e-11: 67: 19.17
+	Hs
		411655 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		BCAR1_HUMAN (7-431): 2.78e-12: 71.7: 21.40
+	Rn
		1144044 FYN_RAT (6-160): 4.4e-46: 159: 20.73		BCAR1_RAT (6-431): 4.77e-12: 70.9: 20.23
+	Mm
		763397 FYN_MOUSE (6-160): 4.58e-46: 159: 20.73		BCAR1_MOUSE (7-431): 8.12e-11: 67: 19.17