HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 986
+	Hs
		313540 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		872668 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		1072532 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		872453 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		665621 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		EPHB2_HUMAN (30-983): 0: 1169: 58.47
+	Hs
		665422 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		EPHA3_HUMAN (26-986): 0: 1182: 63.01
+	Hs
		159938 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		160004 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		159937 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		159898 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA3_HUMAN (26-986): 0: 1182: 63.01
+	Hs
		159900 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHB2_HUMAN (30-983): 0: 1169: 58.47
+	Hs
		160216 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA6_HUMAN (5-986): 0: 1140: 57.75
+	Hs
		159899 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA8_HUMAN (30-981): 0: 1107: 57.11
+	Hs
		159897 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		EPHA2_HUMAN (27-986): 0: 1059: 50.36
+	Hs
		435676 FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47
+	Hs
		435647 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47
+	Rn
		94275 F1LUA1_RAT (40-758): 1.09e-60: 231: 11.74		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Rn
		88876 D4A1J6_RAT (222-758): 6.37e-55: 212: 12.60		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Hs
		159843 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		INSR_HUMAN (284-902): 1.29e-145: 470: 25.00
+	Hs
		442874 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		HCK_HUMAN (573-879): 1.08e-66: 235: 41.29