HitPredict

Interactor 1: ATF4 (P18848)
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67)
Gene: ATF4

Interactor 2: CEBPG (P53567)
CCAAT/enhancer-binding protein gamma (C/EBP gamma)
Gene: CEBPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.949

The method score is based on:

Property Details
Experiments 25416956, 32296183, 23661758, 20102225, unassigned1304, 20211142
Identification Methods two hybrid, fluorescent resonance energy transfer, validated two hybrid, peptide array, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_2
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 8 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 351
Hs

1 150
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024