Interactor 1: SEM1 (O94742)
26S proteasome complex subunit SEM1
Gene: SEM1

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 15117943, 16554755, 37968396, 15610744, 16284124, 16338358, 26744777, 18314965, 34161281, 27405762, 31601863, 31848235, 30792173, 15917626, 21658604, 22927375
Identification Methods affinity chromatography technology, biochemical, cross-linking study, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005829 - cytosol
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 89
Sc

1 306
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025